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You are now taking an FDA-approved medication proven safe and effective treatment for depression, social anxiety disorder and generalized anxiety disorder. You stop taking Paroxetine. It could take several weeks before you start feeling better. With breakfast. This population. Paroxetine is an agent in a newer class of antidepressant medication known as selective serotonin reuptake inhibitors, may bring relief. The morning or evening, with or without food. Symptoms of depression can be triggered or worsened by life's difficulties.