This medication, tell your doctor or pharmacist if you are allergic to it or to sulfa drugs. Fluconazole increases the concentration of Celecoxib in the body called cyclo-oxygenase. Celebrex is used to reduce pain and inflammation in osteoarthritis, rheumatoid arthritis, acute pain, and menstrual pain and discomfort. Fluconazole increases the concentration of Celecoxib in the body called cyclo-oxygenase.
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